Expresión de búsqueda: SEQUESTOSOME-1 PROTEIN 
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Descriptor Inglés:   Sequestosome-1 Protein 
Descriptor Español:   Proteína Sequestosoma-1 
Descriptor Portugués:   Proteína Sequestossoma-1 
Sinónimos Inglés:   EBI3-Associated Protein of 60 KDa
EBIAP Protein
Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 Kda
Ubiquitin-Binding Protein p62
EBI3 Associated Protein of 60 KDa
Phosphotyrosine Independent Ligand For The Lck SH2 Domain Of 62 Kda
Sequestosome 1 Protein
Ubiquitin Binding Protein p62  
Categoría:   D12.644.360.024.329
D12.776.094.750
D12.776.157.057.160
D12.776.476.024.422
Definición Inglés:   A multidomain protein that is highly conserved among multicellular organisms. It contains a ZZ-type ZINC FINGER domain, C-terminal UBIQUITIN - associated (UBA) domain, and interacts with many other signaling proteins and enzymes including, atypical PROTEIN KINASE C; TNF RECEPTOR-ASSOCIATED FACTOR 6; subunits of the mTORC1 complex, and CASPASE-8. It functions in AUTOPHAGY as a receptor for the degradation of ubiquitinated substrates, and to co-ordinate signaling in response to OXIDATIVE STRESS. 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   56538 
Identificador Único:   D000071456 

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